Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p002 | (1) | SRF2015

Associations between circulating non-esterified fatty acids and uterine function in postpartum dairy cows

Cheng Zhangrui , Hiu Yiu Yao Veronica , Wathes D Claire

Evidence suggests that excessive non-esterified fatty acid (NEFA) production during postpartum negative energy balance (NEB) increases the risk of uterine infection. The aims of our study were to investigate associations between circulating NEFAs and uterine gene expression in postpartum dairy cows with NEB using microarray and bioinformatics techniques. Mild NEB (n=6) and severe NEB (n=6) in 12 cows were produced using different milking and...

ra0001p293 | (1) | WCRB2014

Non-cytopathic BVDV suppressed innate immune response in bovine endometrial cells exposed to bacterial lipopolysaccharide

Oguejiofor Chike Fidelis , Cheng Zhangrui , Anstaett Olivia , Brownlie Joe , Fouladi-Nashta Ali A. , Wathes D Claire

Introduction: Infection with non-cytopathic BVDV (ncpBVDV) is associated with uterine disease and infertility in dairy cows although the underlying mechanisms are poorly understood. This project investigated the influence of ncpBVDV on innate immunity of the bovine endometrium.Materials and methods: Primary bovine endometrial cells from each of six cows were divided into four groups (Control; LPS; BVDV; BVDV LPS). Cells were infected with ncpBVDV for 4 d...